An AI model developed in 2020 solved a 50 year old problem - Predicting proteins complex structure in humans. What is the model called?

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CBSE Superintendent Official Paper (Held On: 20 Apr, 2025)
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  1. Amino Acido 1
  2. Alpha Fold 2
  3. Human@50
  4. ProFunction 20

Answer (Detailed Solution Below)

Option 2 : Alpha Fold 2
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ST 1: Current Affairs and General Awareness
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Detailed Solution

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The correct answer is Alpha Fold 2.

Key Points

  • AlphaFold 2 is an AI model developed by DeepMind, a subsidiary of Alphabet, in 2020.
  • It solved the long-standing problem of predicting 3D protein structures from their amino acid sequences.
  • AlphaFold 2 demonstrated groundbreaking accuracy in the Critical Assessment of Structure Prediction (CASP14) competition held in 2020.
  • This development has significant implications for drug discovery, biotechnology, and understanding diseases at a molecular level.
  • The algorithm utilizes advanced machine learning techniques, including deep neural networks, to achieve its predictions.

Additional Information

  • Protein Folding Problem
    • Protein folding refers to the process by which a protein chain acquires its functional 3D structure.
    • This structure is crucial for a protein's biological function.
    • Understanding protein folding has been a key challenge in biology for over 50 years.
  • DeepMind and AlphaFold
    • DeepMind is a UK-based AI company acquired by Alphabet Inc. in 2014.
    • AlphaFold is one of DeepMind's flagship projects aimed at solving complex biological problems.
  • Critical Assessment of Structure Prediction (CASP)
    • CASP is a biennial competition that evaluates methods for protein structure prediction.
    • AlphaFold 2 achieved near-experimental accuracy in CASP14, revolutionizing the field.
  • Implications of AlphaFold
    • It accelerates research in areas like drug development and genetic disorders.
    • AlphaFold's predictions are publicly available through the AlphaFold Protein Structure Database.
    • This open-access approach democratizes scientific progress.

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